SOD2 and aspergillosis: In contrast, although deletion of sod1 (cytoplasmic CuZn-superoxide dismutase (SOD) gene) or sod2 (mitochondrial MnSOD gene) but not sod3 (cytosolic MnSOD gene) increased oxidative (menadione) stress sensitivity of A. fumigatus, but even the triple mutant (Δsod1Δsod2Δsod3) had no decreased virulence in murine aspergillosis models [14].