Molecular testing was performed for 38.5% of all the abnormal newborn screens for non-sickling disease and showed a variety of alpha and beta globin variants, such as beta-thalassemia major (Homozygous β0β0), homozygous hemoglobin E (Hb EE), deletional, and non-deletional Hb H disease. The gene discussed is GSTM1; the disease is beta thalassemia.