RBFOX2 and hypoplastic left heart syndrome: Further confirming the causal relationship of RBFOX2 loss of function with HLHS, zebrafish mutants lacking rbfox1l and rbfox2 develop cardiovascular defects similar to those observed in HLHS patients, including the reduced size and disorganized architecture of ventricular cardiomyocytes, an obstructed aorta, and the absence of endocardial cushions [88].