Endothelial dysfunction, hypercoagulability, and inflammation may still be detectable up to 1 year after recovery from COVID-19, as indicated by increased circulating levels of endothelin-1, intercellular adhesion molecule-1 (ICAM-1), IL-6, von Willebrand factor (vWF), D-dimer, and coagulation factor VIII. The gene discussed is EDN1; the disease is endothelial dysfunction.