In the comparison of serum PGE2, LXA4, CRP, and fibrinogen values obtained during the attack and interictal periods in migraine patients with the healthy control group, during both the attack and interictal periods, serum PGE2 and LXA4 values were statistically significantly lower in migraine patients compared to the healthy control group (p < 0.001) (Table 2, Figure 2). This evidence concerns the gene CRP and migraine disorder.