Organic anion-transporting polypeptides (OATPs) are upregulated in various solid tumors, including liver cancer, with SLCO2A1 (OATP2A1) elevated in HCC and liver metastases from colon cancer, while SLCO1B1 expression decreases in liver cancer, showing a reverse trend with cancer grade [128,129]. The gene discussed is SLCO2A1; the disease is malignant colon neoplasm.