When the effect of CRT on IFN-γ, IL6, and TNFα was investigated for patients with locally advanced non-small-cell lung cancer (NSCLC) or glioblastoma multiforme (GBM), TNF-α levels in NSCLC and IFN-γ levels in GBM decreased [67]. This evidence concerns the gene IFNG and non-small cell lung carcinoma.