UCA1 and serous adenocarcinoma: Another important finding of this study was the ability of UCA1 to facilitate cell-to-cell OVV spread in the SKOV3 line overexpressing UCA1, in contrast to the high-grade serous adenocarcinoma OVCAR3 and ES-2 lines displaying a lower UCA1 expression, and being more susceptible to PTX treatment, instead [61].