TNF and rheumatoid arthritis: In addition, ROC curve analysis (Figure 5) confirms the higher IL10 (AUC: 0.799; 95%CI: 0.582–1.0; p = 0.013) and lower TNFA (AUC: 0.813; 95% CI: 0.662–0.963; p = 0.009) expression could be valuable discriminative factors for higher and lower RA activity.