PIGN and hematocrit: We identified three novel loci associated with GD (LSAMP, HNRNPA3P5, and NTN1), one associated with HT (VAT1L), and one associated with a serum selenium concentration >80 μg/L (LINC01544/RNF152/PIGN), which also contributes to the additive increase in serum selenium in the Latvian population.