The dynamics between Natural Killer (NK) cells, Transforming Growth Factor Beta (TGF-β), and Natural-killer group 2, member D (NKG2D) have been researched using blood samples from glioma patients [104], and the effects of Interferon Gamma (IFN-γ) on NK cells have been explored through human GBM tissue samples [105]. Here, IFNG is linked to central nervous system cancer.