Among circumscribed astrocytic gliomas, Pilocytic AS is characterized by mutations in KIAA1549-BRAF, BRAF, and NF1, while High-Grade Astrocytoma with Piloid Features exhibits alterations in BRAF, NF1, ATRX, and CDKN2A/B (methylome). Here, BRAF is linked to astrocytoma (excluding glioblastoma).