Cacna1c is an important gene for several signaling pathways (ASC [51], calcium [61], cAMP [62], cGPM-PKG [63], MAPK [56]), all five types of synapses [73], as well as CMC [51], and the cardiomyopathies (DIL [54] and HCM [55]). The gene discussed is CACNA1C; the disease is cardiomyopathy.