Of all 19,605 quantified genes, the largest increase in ΔREC in LSD was exhibited by Usp31 (ΔREC = 2411%), a potential biomarker [89] for clear cell renal cell carcinoma [90] and Syt11 (ΔREC = 1517%), known for its role in atrial fibrillation [72]. Here, USP31 is linked to atrial fibrillation.