In contrast, the significant regulation of the diabetic cardiomyopathy [50] gene Gsk3b (glycogen synthase kinase 3 beta, x = −1.490, CUT = 1.341) and the purine metabolism [41] gene Gucy1b2 (guanylate cyclase 1, soluble, beta 2; x = 1.490, CUT = 1.426) would have been neglected. Here, GUCY1B2 is linked to diabetic cardiomyopathy.