The expression levels of five miRNAs, specifically miRNA223-3p, miRNA20a-5p, miRNA17-5p, miRNA19a-3p, and miRNA7-5p, were quantified in the peripheral blood of 77 CRC patients, along with the expression of three proteins, PTEN, ERK, and EGFR. This evidence concerns the gene EGFR and colorectal carcinoma.