Considering that lactotroph PitNETs associate with somatic hotspot SF3B1 mutations [14,15,16], tumor DNAs (tDNA) from 6 and cDNAs from 22 TrkAIII RT-PCR positive lactotroph PitNETs were evaluated for the presence of hotspot SF3B1 c.1866 G > T; c. Here, SF3B1 is linked to neoplasm.