IGF2 and fetal growth restriction: TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) is an example of EDCs, and its paternal exposure in pups is found to be related to IUGR due to placental dysfunction and alterations in the expression of Insulin-like Growth Factor 2 (IGF2) through epigenetic changes in the male germ cell line in a mouse model [117,118].