In high-fat diet-induced nonalcoholic steatohepatitis obese mice, the administration of RebA decreased fasting glucose levels and hepatic stress enzymes, such as alanine aminotransferase (ALT) and plasma aspartate aminotransferase (AST) at 15 weeks post-intervention [21]. This evidence concerns the gene GPT and metabolic dysfunction-associated steatohepatitis.