The NaIO3-induced retinal degeneration mock group showed increased expression of Fas, inflammatory cytokines (TNF-α, IL-6, and IL-1β), MCP-1, and macrophages (F4/80), and an elevated M1 (CD11c)/M2 (CD206) macrophage ratio compared with that in the normal mouse group (Figure 3D). This evidence concerns the gene TNF and retinal degeneration.