The injection of CNE2 (NPC cell line)-EBV-positive cells into humanized mice resulted in elevated expression of VEGF and the cytokine granulocyte macrophage-colony stimulating factor (GM-CSF), increased infiltration of CCL18+ macrophages, the emergence of an EMT-like phenotype, and elevated rates of lung metastasis when administered subcutaneously [105,106]. The gene discussed is CSF2; the disease is nasopharyngeal carcinoma.