Migration and invasion were also promoted by TRAIL in NSCLC the A549 cell line in a RIPK1-dependent manner through phosphorylation of Src and STAT3 [12], in pancreatic ductal adenocarcinoma [11], in colorectal cancer cells, resistant [346] or not [114] to TRAIL-induced cell death and in the triple-negative breast cancer cell line MDA-MB-231 (TNBCs) [114]. Here, TNFSF10 is linked to pancreatic ductal adenocarcinoma.