TIMP1 and pulmonary fibrosis: To characterize the kinetic effects of 2 U/kg i.t. bleomycin on various biochemical markers of lung fibrosis, we measured the concentrations of TGFβ1, IL6, TNFα, IL1β, CINC1, WISP1, VEGF, and TIMP1 in BALF at days 3, 7, and 14 following instillation.