Given the implication of RBM8A in several neurodevelopmental disorders, as well as the critical role of astrocytes in their pathogenesis, we explored how Rbm8a haploinsufficiency in astrocytes modulates animal behaviors using a novel mouse model carrying conditional heterozygous deletion of the Rbm8a gene, which may provide some insights into the role of astrocytes in neurodevelopmental disorders. The gene discussed is RBM8A; the disease is neurodevelopmental disorder.