CHRNA4 and Parkinson disease: Thus, given the important role of glial cells in the pathogenesis of PD [17,18,19,20] and the implicated nAChR regulation of these cells [17,18,21], our aim in this review is to provide not only an update on glial nAChRs’ role in glial function but also the potential exploitation of this knowledge in identifying novel targets for this devastating disease.