Based on our literature research [24] and our recent findings [25], two promising protein biomarkers, v-set and immunoglobulin domain containing-4 (VSIG4) and TNF receptor superfamily member 1 (BTNFRSF1b), were selected for the development of the smartphone-based multiplexed biomarker detection platform for lupus nephritis (LN). Here, VSIG4 is linked to lobular neoplasia.