Biologically, according to the CAPS Registry, LA was found in 83% of proven CAPS cases, aCL IgG in 81%, aCL IgM in 49%, anti-β2-GP1 IgG in 78%, and anti-β2GP1 IgM in 40% of cases [10] (Table S1). The gene discussed is APOH; the disease is cryopyrin-associated periodic syndrome.