NEFL and nasopharyngeal carcinoma: GFAP levels were not elevated in NPC (66.6 vs. 75.1 pg/ml).<h4>Discussion</h4>The study adds important evidence on the potential diagnostic utility of plasma NfL in NPC, extends the literature of NfL as a diagnostic tool to differentiate neurodegenerative from primary psychiatric disorders, and adds support to the pathology in NPC primarily involving neuronal, particularly axonal, degeneration.