GUCY2C and colorectal carcinoma: TAAs in CRC include Carcinoembryonic antigen (CEA) and melanoma-associated antigen (MAGE), mucin 1 (MUC-1), epidermal growth factor receptor (EGFR), vascular endothelial growth factor receptor 1 and 2 (VEGFR1, VEGFR2), transmembrane 4 superfamily member 5 protein (TM4SF5), survivin, mitotic centromere-associated kinesin (MCAK), guanylyl cyclase C (GUCY2C), and 5T4 (16).