cDC-2 express various markers such as IRF4, CD11b, SIRPα, CLEC10A, and CD1C, and produce IL-1β, IL-6, IL-8, IL-12, TFN-α, CCL3, and CXCL8 to activate anti-tumor T cell responses (143, 144). This evidence concerns the gene CXCL8 and neoplasm.