On the other hand, the top three immune traits with the largest OR values among the risk factors for esophageal cancer were “CD86+ plasmacytoid DC %DC” (IVW p =0.039; OR=1.198, 95%CI [1.009-1.422]), “CD38 on PB/PC” (IVW p =0.047; OR=1.220, 95%CI [1.003-1.483]), and “CD86+ plasmacytoid DC AC” (IVW p =0.036; OR=1.260, 95%CI [1.015-1.563]). The gene discussed is CD86; the disease is esophageal cancer.