The results showed that age [odds ratio (OR) 95% confidence interval (CI) = 1.087 (1.042–1.135), p < 0.001], Cys C [OR (95%CI) = 23.065 (1.216–437.417), p = 0.037], Lp-PLA2 activity [OR (95%CI) = 1.006 (1.002–1.010), p = 0.006] were all significantly associated with PD-CI, and higher levels of GFR might be a protective factor for PD-CI [OR (95%CI) = 0.956 (0.926–0.987), p = 0.006]. This evidence concerns the gene PLA2G7 and Parkinson disease.