Lp-PLA2 mainly produces Lys phosphatidylcholine (lysoPC) and oxidized non-esterified fatty acids (oxNEFAs) by hydrolyzing oxidized LDL (ox-LDL) to exert pro-inflammatory effects, thereby participating in the occurrence and development of atherosclerosis, as well as plaque stability and plaque rupture (Huang et al., 2020). This evidence concerns the gene PLA2G7 and atherosclerosis.