Current evidence from our study showed that higher levels of inflammatory markers, such as CRP, LDH, D-dimer, and ferritin, are associated with the severity of COVID-19 in terms of ARDS and thus could be used as significant prognostic factors of the disease. According to our study, the most sensitive marker that correlated with ARDS is D-dimer and the most specific was CRP. The gene discussed is CRP; the disease is acute respiratory distress syndrome.