Consistent with previous reports, the sFlt-1/PlGF ratio showed better diagnostic power for early-onset preeclampsia than for late-onset preeclampsia, and the AUC of the sFlt-1/PlGF ratio from the test kit was 0.857 for early onset (15 cases, 21 controls) and 0.781 for late-onset (27 cases, 21 controls) in the discovery set (Fig. 3A and B). This evidence concerns the gene PGF and preeclampsia.