In boys with a history of bilateral cryptorchidism, particularly in those who underwent orchiopexy, higher FSH and lower inhibin B levels than those of non-cryptorchid boys from 0.5–1 year after pubertal onset to the time of full pubertal maturation were shown, indicating decompensated Sertoli cell and/or germ cell dysfunction and/or more severely decreased number of these cells in bilateral cryptorchidism (42). This evidence concerns the gene BRD2 and cryptorchidism.