Consistent with the oncogenic and pro-angiogenic role of TRPM2-AS in GBC cells, RT-qPCR (Fig. S3A), western blot (Fig. S3B), and immunohistochemistry (Fig. S3C) also showed that the expression level of IGF2BP2 was increased in tumor tissues, especially in those with high microvascular density. Here, TRPM2 is linked to neoplasm.