Moreover, lncRNAs can also act as competitive endogenous RNAs (ceRNAs) to compete with target genes for miRNAs to influence the course of DCM [17, 18], including NLRP3 inflammasome activation-mediated pyroptosis [19], cardiac fibrosis and hypertrophy [20, 21], as well as cardiomyocyte apoptosis by epigenetic regulation of target genes [22]. This evidence concerns the gene NLRP3 and familial dilated cardiomyopathy.