The incidence of significant liver inflammation was detected in 78.3% and 75.5% of patients with aged < 30 years and aged ≥ 30 years, and in 63.0%, 76.7% and 88.3% of patients with ALT < 1 × ULN, 1–2 × ULN, and ≥ 2 × ULN, respectively (Fig. 2C). The gene discussed is GPT; the disease is Hepatitis.