KDR and neoplasm: In the mouse H22 tumor model, the expression levels of VEGF A, VEGFR2 and p-VEGFR2 were lower in groups B and C than in group A (P < 0.05), whereas in group D, the expression levels of VEGFA and VEGFR2 were significantly lower than in groups A and C (P < 0.05) (Fig. 3(1–8)).