JAK2 and acute myeloid leukemia: Moreover, a few demographic (age, white race, and Asian race), clinical (secondary AML, blasts, Hbg, and serum B2M), cytogenetic (complex karyotype, −5/5q-, −7/7q-, t(8;21), Inv16, and Del12), and mutational (ASLX1, CEBPA, FLT3 [individually for ITD and D835, and in combination], IDH2, JAK2, MLL, NPM1, PTPN11, and TP53 mutations) features were also prognostic in the UV model for OS.