Notably, METTL3-induced m6A interacted with ncRNAs to improve glycolysis, such as stabilizing effects on lncRNA ABHD11-AS1 in NSCLC,227 lncRNA SNHG7 in prostate cancer (PC),228 circQSOX1 in CRC,229 and linc-UROD in PC,230 which are generally mediated by IGF2BPs. Here, METTL3 is linked to pachyonychia congenita.