Results of GSEA as revealed from the prostate cancer patients derived from TCGA database (Fig. 2C) and the expression patterns of representative EMT biomarkers in NURR1-overexpression prostate cancer cells (Fig. 5C) suggest that NURR1 could play a supportive role in EMT regulation in prostate cancer cells. This evidence concerns the gene NR4A2 and Familial prostate cancer.