KMT2A and acute myeloid leukemia: Notably, TOP2‐associated t‐AL cases often harbour characteristic balanced chromosome translocations [3] including those involving the KMT2A/MLL locus or t(15,17)(PML‐RARA), t(8,21)(AML/RUNX1‐ETO) and inv(16)(MYH11‐CBFB) translocations [7].