SHBG and Insulin resistance: All of the unfavorable adiposity clusters (BFP-C1, C2, and C3 and BMI-C1 and C2) were associated with an adverse metabolic profile (higher triglycerides, C-reactive protein, liver enzymes, insulin resistance, and lower HDL-cholesterol and sex-hormone binding globulin) while favorable adiposity clusters (BFP-C4 and C5 and BMI-C3) were associated with a favorable metabolic profile (Fig. 2).