Reciprocal changes were seen to IFN receptor knockout studies (Fig. 4), with IFN-λ promoting recruitment/retention of M2 macrophages, CD11b+CD11c+ interstitial macrophages, and ciliated epithelial cells while IFN-β promoted pDC recruitment by day 1 post-infection (Fig. 8F). The gene discussed is IFNB1; the disease is infection.