We observed that PLS1 gene expression weights were positively correlated with case–control t values, implying that positively (or negatively) weighted PLS1 genes were overexpressed in increased (or decreased) regional MS in PD patients compared to controls (Pearson's r = 0.53, p < 0.001; Figure 3B). The gene discussed is PLS1; the disease is myeloid sarcoma.