EGFR and asthma: Loss of the superficial epithelial layer, preferential destruction of ciliated cells, and over expression and activation of EGFR with increases in growth factors, including TGFβ (Hoshino et al., 1998; Shahana et al., 2005; Boxall et al., 2006; Holgate, 2007), are found in the majority of asthma suffers; even occurring in mild, early, and non-fatal asthma.