GCG and type 2 diabetes mellitus: The accumulation ratios of Rmax and AUEC0-24 h for plasma active GLP-1 in 50 mg cetagliptin, 100 mg cetagliptin, and sitagliptin groups were about 1.5 in patients with T2DM, and about 1.0 in healthy subjects, indicating that patients with T2DM were more sensitive to drugs.