In summary, this investigation proposes that the combination of FNA and FNA-Tg holds significant diagnostic value in the identification of LNM in DTC.Factors such as TNM stage indicated N1b, the presence of HVLNM, lymph node L/S, liquefaction, calcification, tumor diameter, the presence of HT, sTg, and sTgAb can influence FNA-Tg levels. Here, TG is linked to neoplasm.