The extent of platelet activation influences several effector factors, such as Vascular Endothelial Growth Factor (VEGF), Platelet-derived growth factor (PDGF), and transforming growth factor-β (TGF-β), which influence vascular maturation in the tumor microenvironment and mediate cancer cell invasion (61), which are associated with the survival rate of BC patients. Here, TGFB1 is linked to breast cancer.