KLK3 and posterior cortical atrophy: At present, although prostate specific antigen (PSA), PSA density (PSAD), multi-parameter magnetic resonance imaging (mpMRI), prostate specific membrane antigen positron emission tomography/computed tomography (PSMA PET/CT) and other detection methods have played an important role in the diagnosis of PCa, but the gold standard for the diagnosis of PCa is still prostate biopsy (4–6).