ACE and Hyperkalemia: A European study reported higher MRP rates, with the most frequent potentially severe DDIs being psychotropic drugs with additive effects on QTc prolongation, associations of angiotensin-converting enzyme inhibitors or angiotensin II receptor blockers with potassium supplements, increasing the risk of hyperkalemia, and SSRI/SNRI with antiplatelets, increasing the risk of hemorrhage (Pasina et al., 2020).