For example, previous work has linked GR to N-methyl-D-aspartate receptor (NMDAR) activity in the hippocampus, which is known to contribute to TBI-induced excitotoxicity and cognitive deficits (Zhang et al., 2012; Baracaldo-Santamaría et al., 2022). The gene discussed is NR3C1; the disease is Cognitive impairment.